IgG4-Related Sialadenitis

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منابع مشابه

IgG4 related sclerosing sialadenitis- a retrospective analysis.

BACKGROUND IgG4 related disease rarely affects the salivary glands and clinically is often confused with salivary gland malignancy. METHOD This is a retrospective study comprising 137 cases of chronic sialadenitis diagnosed in a histopathology department over 4 years. The morphology was assessed by reviewing the histology slides and the incidence of IgG4 related sclerosing sialadenitis was ca...

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IgG4-related sialadenitis: IgG4 is helpful, but biopsies are still crucial

IgG4-related disease is rare, but a frequent differential diagnosis for malignant and for autoimmune diseases. Li and colleagues report the largest cohort of patients with IgG4-related sialadenitis. The observations reveal that the most important diagnostic step is obtaining biopsies. In addition, the IgG4 serum concentration may be a biomarker for the disease progression.

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Chronic sclerosing sialadenitis as the initial manifestation of the IgG4-related sclerosing disease

Three Chinese patients, one female aged 63 years, two males aged 52 and 54 years, respectively, all presented with chronic sclerosing sialadenitis (CSS) as the initial clinical manifestation, followed by IgG4-related sclerosing pancreatitis. The kidneys and lungs were involved in case 1. Moreover, enlargement of hilar lymph nodes was also noted in this patient. After steroid therapy, the clinic...

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Comorbid diseases of IgG4-related sialadenitis in the head and neck region.

OBJECTIVES/HYPOTHESIS To further recognize the comorbid diseases of immunoglobulin G4-related sialadenitis (IgG4-RS) in the head and neck region and to observe the response of these conditions to immunomodulatory therapy. STUDY DESIGN Retrospective review. METHODS The symptoms of comorbid diseases and medical histories in 51 patients (24 men, 27 women; median age, 55 years) diagnosed with I...

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Roles of IL-17, Th1, and Tc1 cells in patients with IgG4-related sclerosing sialadenitis.

OBJECTIVES/HYPOTHESIS Immunoglobulin G4 (IgG4)-related sclerosing sialadenitis is a recently recognized disease entity characterized by high serum IgG4 concentration and IgG4-producing plasma cell expansion in affected organs, which show fibrotic or sclerotic changes. However, little is known about the roles of CD4+ and CD8+ T cells or interleukin (IL)-17 in this disease. The purpose of this st...

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ژورنال

عنوان ژورنال: Ear, Nose & Throat Journal

سال: 2019

ISSN: 0145-5613,1942-7522

DOI: 10.1177/0145561319890153